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Causal
Agent:
The cestode (tapeworm)
Taenia solium (pork tapeworm) is the main cause of human cysticercosis.
In addition, the larval stage of other Taenia species (e.g., multiceps, serialis,
brauni, taeniaeformis, crassiceps) can infect humans
in various sites of localization including the brain, subcutaneous tissue,
eye, or liver.
Life
Cycle:

Cysticercosis
is an infection of both humans and pigs with the larval stages of the
parasitic cestode, Taenia solium. This infection is caused by
ingestion of eggs shed in the feces of a human tapeworm carrier
.
Pigs and humans become
infected by ingesting eggs or gravid proglottids
.
Humans are infected either by ingestion of food contaminated with feces,
or by autoinfection. In the latter case, a human infected with adult
T. solium can ingest eggs produced by that tapeworm, either through fecal
contamination or, possibly, from proglottids carried into the stomach by
reverse peristalsis. Once eggs are ingested, oncospheres hatch in
the intestine
,
invade the
intestinal wall, and migrate to striated muscles, as well as the brain,
liver, and other tissues, where they develop into cysticerci. In humans, cysts can cause serious sequellae if they
localize in the brain, resulting in neurocysticercosis. The parasite
life cycle is completed, resulting in human tapeworm infection, when
humans ingest undercooked pork containing cysticerci
.
Cysts evaginate and attach to the small intestine by their scolex
.
Adult tapeworms develop, (up to 2 to 7 m in length and produce less than
1000 proglottids, each with approximately 50,000 eggs) and reside in the
small intestine for years
.
Geographic
Distribution:
Taenia solium
is found worldwide. Because pigs are intermediate hosts of the parasite,
completion of the life cycle occurs in regions where humans live in close
contact with pigs and eat undercooked pork. Taeniasis and cysticercosis
are very rare in Muslim countries. It is important to note that
human cysticercosis is acquired by ingesting T. solium eggs shed
in the feces of a human T. solium tapeworm carrier, and thus can
occur in populations that neither eat pork nor share environments with
pigs.
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