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Special
Tests: MQ Testing
Mefloquine is
recommended by CDC as a prophylactic against malaria. When individuals
who are presumably on mefloquine prophylaxis exhibit signs of malaria,
blood samples are collected and analyzed for the presence of the drug. The drug is extracted from the blood and the concentration is determined
by high-performance liquid chromatographic methods. Determining
the level of mefloquine in the blood helps assess if the individual was
adherent with his/her medication. This procedure is also useful
to determine treatment failure due to a mefloquine resistant form of malaria.
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