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Causal Agent:
Metagonimus yokogawai, a
minute intestinal fluke (and the smallest human fluke).
Life Cycle:

Adults release
fully embryonated eggs each with a fully-developed miracidium, and eggs are passed in the host’s feces
.
After ingestion by a suitable snail (first intermediate host),
the eggs hatch and release miracidia which penetrate the snail’s intestine
.
Snails of the genus Semisulcospira are the most frequent intermediate host
for Metagonimus yokogawai. The miracidia undergo several developmental
stages in the snail, i.e. sporocysts
, rediae
,
and cercariae
. Many cercariae are produced from each redia.
The cercariae are released from the snail
and encyst as metacercariae in the
tissues of a suitable fresh/brackish water fish (second intermediate host)
.
The definitive host becomes infected by ingesting undercooked or salted fish containing metacercariae
.
After ingestion, the metacercariae excyst, attach to the mucosa of the small
intestine
and mature into adults (measuring 1.0 mm to 2.5 mm by 0.4 mm to 0.75 mm)
. In addition to humans, fish-eating mammals
(e.g., cats and dogs) and birds can also be infected by
M. yokogawai
.
Geographic
Distribution:
Mostly the Far East, as well as
Siberia, Manchuria, the Balkan states, Israel, and Spain.
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