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Amebiasis
[Entamoeba histolytica]
E. histolytica/dispar trophozoite line drawing E. histolytica/dispar trophozoite E. histolytica/dispar trophozoite E. histolytica/dispar trophozoite
A B C D

A, B, C, D: Trophozoites of Entamoeba histolytica/dispar, line drawing (A) and trichrome stain (B, C, and D).
(Reminder: in the absence of erythrophagocytosis, the pathogenic E. histolytica is morphologically indistinguishable from the nonpathogenic E. dispar!)  Each trophozoite has a single nucleus, which has a centrally placed karyosome and uniformly distributed peripheral chromatin.  This typical appearance of the nucleus is not always observed: some trophozoites can have nuclei with an eccentric karyosome and unevenly distributed peripheral chromatin.  The cytoplasm has a granular or "ground-glass" appearance.  Entamoeba histolytica/dispar trophozoites measure usually 15 to 20 µm (range 10 to 60 µm), tending to be more elongated in diarrheal stool.  B: Specimen contributed by Dr. Ray Kaplan, SmithKline Beecham, Atlanta, GA.

 

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