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[Entamoeba histolytica]

A	B

A, B: Endolimax nana trophozoites.  The trophozoites each have one nucleus with a characteristically large, irregularly shaped, blot-like karyosome (line drawing, A; trichrome stain, B).  Their nucleus has no peripheral chromatin.  Their cytoplasm is granular and vacuolated.  The trophozoites measure usually 8 to 10 µm (range 6 to 12 µm).