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Malaria
[Plasmodium falciparum] [Plasmodium malariae]
[Plasmodium ovale] [Plasmodium vivax]

Plasmodium falciparum: Trophozoites

Smears from patients:

Although rarely seen in peripheral blood smears, older, ring stage parasites are referred to as trophozoites.  The cytoplasm of mature trophozoites tends to be thicker and more dense than in younger rings.  As P. falciparum trophozoites grow and mature, they tend to retain their ring-like shape and sometimes trace amounts of yellow pigment can be seen within the cytoplasm.  Growing trophozoites in P. falciparum can appear slightly amoeboid in shape.

Trophozoites of P. falciparum in a thin blood smear Trophozoites of P. falciparum in a thin blood smear
A B

A: Appliqué trophozoite: Note the slight amoeboid appearance of the parasite.
B: A larger, more mature trophozoite and smaller, younger ring stage parasites in a thin blood smear.

Trophozoites of P. falciparum in a thin blood smear Trophozoites of P. falciparum in a thin blood smear
C D

 C, D: More mature and compact trophozoites.  Note the presence of pigment in C.

 

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