There is no established specific therapy for human cryptosporidiosis.  Rapid loss of fluids because of diarrhea can be managed by fluid replacement and electrolyte balance.  Infection in healthy, immunocompetent persons is self-limited, but infection in immunocompromised persons and those in poor health are at higher risk for more severe illness.  For persons with AIDS, anti-retroviral therapy, which improves immune status, will also decrease or eliminate.   Paromomycin is approved for treatment.

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